Reading could yet return to the top flight along with Newcastle, who only need four points from their remaining four matches to seal the title.
With 10 wins from their last 17 matches, in-form Reading have been transformed from relegation candidates to play-off hopefuls since Brian McDermott was handed the job of manager.
They are nine points away from the top six, but have two games in hand on their rivals. However, one of those is against a Newcastle side whose record this season speaks for itself. The Royals final matches are against struggling sides: Peterborough, Preston, Scunthorpe and Watford.
Reading will be without central defender Matt Mills.
The Royals captain is serving a four-match suspension after an appeal against his recent sending off at Ipswich Town was rejected.
Newcastle will assess the fitness of Jose Enrique, who could return to the side after missing Saturday's 4-1 victory against Blackpool with a virus.
Tamas Kadar, who replaced Enrique at the weekend, has been ruled out because of a thigh strain.
I have to say we are on the highest of form in the moment and clinching this title would be a definite thing. Hope hughton would make wise transfer movemrnts this window and ensure that the players who are here wants to fight and not for the money.
2-0 to us at the majeski stadium! I predict 1 or 2 more from us! 4-0 newcastle!